The authors have developed a text book Genetics: From Genes to Genomes that reflects the directions Genetics is taking as it heads into the 21st century. This perspective embraces five major 1. the central importance of the genome, as opposed to the action of individual genes;

2. the application of genetics to the improvement of human health;

3. the growing appreciation for the relationships among organisms arising from genetic research;

4. the impact of biotechnology on the accelerating growth of genetic knowledge; and

5. the importance of emerging social and ethical issues related to our use of biotechnology.

The book is designed with students in mind, offering numerous features to support learning. Each chapter includes summaries, key terms, and review questions, which help reinforce the material. The accompanying online resources provide additional support, including interactive tools and further readings, making this textbook a versatile tool for both in-class and independent study.

Contents

Part I: Basic Principles: How Traits Are Transmitted

  • Mendel’s Principles of Heredity
  • Extensions to Mendel’s Laws
  • Chromosomes and Inheritance
  • Sex Chromosomes
  • Linkage, Recombination, and Gene Mapping

Part II: What Genes Are and What They Do

  • DNA Structure, Replication, and Recombination
  • Mutation
  • Using Mutations to Study Genes
  • Gene Expression: The Flow of Information from DNA to RNA to Protein

Part III: Analysis of Genetic Information

  • Digital Analysis of DNA
  • Genome Annotation
  • Analyzing Genomic Variation

Part IV: How Genes Travel on Chromosomes

  • The Eukaryotic Chromosome
  • Chromosomal Rearrangements
  • Ploidy
  • Bacterial Genetics
  • Organellar Inheritance

Part V: How Genes Are Regulated

  • Gene Regulation in Prokaryotes
  • Gene Regulation in Eukaryotes
  • Epigenetics

Part VI: Using Genetics

  • Manipulating the Genomes of Eukaryotes
  • Genetic Analysis of Development
  • The Genetics of Cancer

Part VII: Beyond the Individual Gene and Genome

  • Variation and Selection in Populations
  • Genetic Analysis of Complex Traits

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