Concepts of Genetics emphasises the fundamental ideas of genetics, while exploring modern techniques and applications of genetic analysis. This best-selling text continues to provide understandable explanations of complex, analytical topics and recognises the importance of teaching students how to become effective problem solvers.
The 12th Edition has been extensively updated to provide comprehensive coverage of important, emerging topics such as CRISPR-Cas and the study of posttranscriptional gene regulation in eukaryotes. An expanded emphasis on ethical considerations that genetics is bringing into everyday life is addressed in Genetics, Ethics, and Society and Case Study features.
Contents
Part I: Genes, Chromosomes, and Heredity
- Introduction to Genetics
- Mitosis and Meiosis
- Mendelian Genetics
- Extensions of Mendelian Genetics
- Chromosome Mapping in Eukaryotes
- Genetic Analysis and Mapping in Bacteria and Bacteriophages
- Sex Determination and Sex Chromosomes
- Chromosome Mutations: Variation in Number and Arrangement
- Extranuclear Inheritance
Part II: DNA: Structure, Replication, and Organization
- DNA Structure and Analysis
- DNA Replication and Recombination
- DNA Organization in Chromosomes
Part III: Gene Expression and Its Regulation
- The Genetic Code and Transcription
- Translation and Proteins
- Gene Mutation, DNA Repair, and Transposition
- Regulation of Gene Expression in Bacteria
- Transcriptional Regulation in Eukaryotes
- Posttranscriptional Regulation in Eukaryotes
- Epigenetic Regulation of Gene Expression
Part IV: Genetic Technology and Genomics
- Recombinant DNA Technology
- Genomic Analysis
- Applications of Genetic Engineering and Biotechnology
Part V: Genetic Analysis of Organism and Populations
- Developmental Genetics
- Cancer Genetics
- Quantitative Genetics and Multifactorial Traits
- Population and Evolutionary Genetics
Special Topics in Modern Genetics
- CRISPR and Genomic Editing
- DNA Forensics
- Genomics and Precision Medicine
- Genetically Modified Foods
- Gene Therapy
- Advances in Neurogenetics: The Study of Huntington Disease
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